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Updated: May 4, 2026

Induction of Ocular Surface Inflammation and Collection of Involved Tissues
Published on: August 4, 2022
A case of eosinophilic myositis associated with orbital myositis
M Nakashima1, Y Kawabe, T Aoyagi
1Department of Rheumatology, National Ureshino Hospital , 2436 Shimojuku Hei, Ureshino-machi, Fujitsu-gun, Saga 843-0393 , Japan.
Abstract:
Abstract A 29-year-old woman was admitted to our hospital because of fever, myalgia, and ocular pain. She had been given norgesterone and ethinylestradiol orally. Laboratory data indicated the presence of systemic inflammation together with elevated levels of muscle enzymes. Magnetic resonance imaging revealed inflammatory lesions in skeletal and extraocular muscles. The diagnosis of eosinophilic myositis was based on histopathological examination of the deltoid muscle, which showed infiltration of eosinophils into the tissue with necrotizing muscle fibers. Prednisolone treatment resulted in marked clinical improvement. This is the first case report of eosinophilic myositis in which the extraocular muscles were affected.
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