Related Experiment Video
Updated: May 4, 2026
04:47
Author Spotlight: Evaluating Traditional Chinese Therapy for Ankylosing Spondylitis in Mice
Published on: October 27, 2023
2.2K
Ankylosing spondylitis associated with vitiligo: a case report.
1Division of Clinical Immunology and Hematology, Department of Medicine, Sapporo City General Hospital , Kita 11, Nishi 13, Chuo-ku, Sapporo 060-8604 , Japan.
Modern Rheumatology
|January 4, 2014
Summary
Vitiligo and ankylosing spondylitis (AS) are both suspected autoimmune diseases. This case report suggests a potential shared autoimmune background linking these two distinct conditions.
Area of Science:
- Immunology
- Dermatology
- Rheumatology
Background:
- Vitiligo is a common autoimmune skin condition.
- Ankylosing spondylitis (AS) is an inflammatory disease with suspected autoimmune origins.
- Autoimmune complications are frequently observed alongside vitiligo.
Purpose of the Study:
- To report a case of concurrent vitiligo and ankylosing spondylitis (AS).
- To explore the potential common autoimmune pathogenesis between vitiligo and AS.
Main Methods:
- Case report of a 56-year-old male patient.
- Clinical observation and diagnostic assessment for both vitiligo and AS.
Main Results:
- The patient presented with both vitiligo and ankylosing spondylitis.
- This co-occurrence supports the hypothesis of shared underlying autoimmune mechanisms.
Conclusions:
- Vitiligo and ankylosing spondylitis may share a common autoimmune etiology.
- Further research is warranted to elucidate the specific links between these autoimmune diseases.
Related Concept Videos
01:23Skin Diseases and Disorders
5.4K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.4K
01:14Changes in Skin Color: Clinical Perspectives
3.6K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
3.6K
01:22Connective Tissue Cell Types
3.4K
Connective tissue develops from the mesoderm of a developing embryo and consists of cells, fibers, and ground substance: a gel-like material containing large complexes of carbohydrates and proteins. Connective tissue was first identified as a separate tissue family in the 18th century, and Johannes Peter Muller coined the term connective tissue.
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...
3.4K
01:20Inflammatory Bowel Disease IV: Clinical Manifestations
33
Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The...
33
01:29Autoimmune Disorders
2.4K
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
Concept and Mechanism of Autoimmune Diseases
The immune...
2.4K
01:23Role of Skin in Vitamin D Synthesis
8.1K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
8.1K