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The Year in Cardiology 2013: valvular heart disease (focus on catheter-based interventions)
Eberhard Grube1, Jan-Malte Sinning, Alec Vahanian
1Department of Medicine II, Heart Center Bonn, University Hospital Bonn, Sigmund-Freud-Str. 25, 53105 Bonn, Germany.
Insights
Transcatheter heart valve interventions are expanding, but complex decisions remain for patients with valvular heart disease (VHD). Randomized trials are needed to support expanding less invasive treatments to intermediate-risk patients.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- The multidisciplinary heart team approach is now standard for valvular heart disease (VHD) management, influenced by 2012 European guidelines.
- Transcatheter heart valve interventions gained prominence in 2013.
- Managing VHD in elderly patients presents complexity due to high rates of co-morbidity and frailty.
Purpose of the Study:
- To discuss the complex decision-making process for valvular heart disease (VHD) patients.
- To highlight the challenges in expanding transcatheter interventions to intermediate-risk populations.
- To emphasize the need for evidence from randomized clinical trials.
Main Methods:
- Review of current guidelines and clinical practice in VHD management.
- Analysis of patient selection criteria for surgical versus transcatheter interventions.
- Discussion of the role of the heart team in complex VHD cases.
Main Results:
- Decision-making for VHD patients who are poor surgical candidates but not yet suitable for catheter intervention is challenging.
- The prevalence of co-morbidity and frailty in older VHD patients complicates treatment choices.
- Current evidence primarily supports transcatheter interventions in high-risk surgical patients.
Conclusions:
- Transcatheter aortic valve implantation (TAVI) and similar interventions require further randomized trial data before wider adoption in intermediate-risk VHD patients.
- The heart team approach is crucial for optimizing VHD patient care.
- Future research should focus on generating robust evidence for less invasive VHD treatments.
Abstract:
2013 was the year of transcatheter heart valve interventions. Not least because of the 2012 European guidelines on the management of valvular heart disease (VHD), the multidisciplinary heart team approach became an established concept. Decision-making, when a patient is too 'sick' for surgery and too 'healthy' for catheter-based interventions, is complex, since VHD is often seen at an older age and, as a consequence, there is a higher frequency of co-morbidity and frailty. However, before TAVI and other transcatheter heart valve interventions can be expanded to intermediate-risk patients, evidence in favour of this less invasive treatment has to be provided by upcoming randomized clinical trials.
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