Related Experiment Video
Updated: Aug 28, 2026

09:01
Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
Published on: March 26, 2018
[Differentiation of human malignant myeloid and lymphoid cells]
Abstract:
In vitro differentiation of malignant cells was obtained with various agents such as DMSO, retinoids, and low concentrations of ARA-C. In vivo treatment with low dose ARA-C in acute non-lymphoblastic leukemia, especially in elderly patients, induced complete remissions. Interferon was active in hairy cell leukemia, not through cytotoxic cell activation but by a direct effect on cell growth of the hairy cells and changes in the expression of some genes.

