On the theory of the measurement of the first-pass pulmonary extraction using the indicator dilution technique

Theory and concept of extraction involving invasive as well as non-invasive procedures to assess the first-pass extraction of tracers based on the indicator dilution technique are discussed. The experimental result of a non-invasive method using a gamma scintillation camera-computer system of first-pass pulmonary extraction of N-Isopropyl-123I-p-Iodoamphetamine (123I-IMP) are also discussed.