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Related Concept Videos

Glaucoma: Overview01:25

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Related Experiment Video

Updated: May 4, 2026

A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion
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[Ocular ischemic syndrome--a case report].

M Zemba1, Corina Ioana Avram1, Uliana Ochinciuc1

  • 1Spitalul Universitar de Urgenţă Militar Central Dr. Carol Davila Bucureşti.

Oftalmologia (Bucharest, Romania : 1990)
|January 7, 2014
PubMed
Summary
This summary is machine-generated.

Ocular ischemic syndrome, a rare condition from reduced blood flow to the eye, can cause severe vision loss. Early diagnosis and treatment, like laser panphotocoagulation, are crucial for managing this hypoperfusion retinopathy.

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Area of Science:

  • Ophthalmology
  • Vascular Medicine
  • Neurology

Background:

  • Ocular ischemic syndrome (OIS) is a rare condition caused by chronic arterial hypoperfusion affecting the central retinal artery and ciliary arteries.
  • It is often bilateral and frequently linked to severe carotid artery occlusion, as described by Kearns and Hollenhorst.
  • Risk factors include age (50-80), male gender, hypertension, diabetes, coronary disease, and stroke.

Observation:

  • A 63-year-old male with hypertension, hypercholesterolemia, type 2 diabetes, and a history of stroke presented with bilateral visual impairment.
  • Imaging revealed significant carotid artery occlusion.
  • Ophthalmologic evaluation showed ocular hypertension and rubeosis iridis in the right eye, and optic atrophy in both eyes.

Findings:

  • The patient was diagnosed with chronic ocular ischemic syndrome in both eyes.
  • Specific diagnoses included neovascular glaucoma in the right eye and anterior ischemic optic neuropathy in the left eye.
  • Superior altitudinal visual field defect was noted in the left eye.

Implications:

  • This case highlights the severe visual consequences of carotid artery disease on ocular health.
  • Prompt diagnosis and intervention, such as laser panphotocoagulation, are vital for managing OIS and its complications.
  • Understanding the link between systemic vascular disease and OIS is critical for comprehensive patient care.