Dextromethorphan for neuropathic pain with Churg-Strauss syndrome
M Harada1, R Kuwahara, H Yoshida
1Second Department of Medicine, Kurume University School of Medicine , 67 Asahi-machi, Kurume 830-0011 , Japan.
Abstract:
Abstract A 48-year old man who had been treated with prednisolone, aminophylline, and pranlukast, a leukotriene-receptor antagonist, was diagnosed with Churg-Strauss syndrome based on the findings of asthma, eosinophilia, mononeuropathy, and extravascular eosinophils. Intractable neuropathic pain of the legs was successfully controlled with an N-methyl-d-aspartate receptor antagonist, dextromethorphan. We suggest that dextromethorphan receptor antagonists may be a useful treatment for the pain of neuropathy caused by vasculitis syndrome.
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