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Updated: May 4, 2026

Anti-Nuclear Antibody Screening Using HEp-2 Cells
Published on: June 23, 2014
A case of rheumatoid arthritis that developed autoimmune hepatitis associated with anti-Golgi complex antibody
Makoto Okada1, Kimihiro Suzuki, Shinji Miyamoto
1Internal medicine I, National Defense Medical College , 3-2 Namiki, Tokorozawa 359-8513 , Japan.
Abstract:
Abstract A 50-year-old woman, who had been diagnosed as having rheumatoid arthritis (RA) 7 months earlier, was admitted to our hospital because of liver dysfunction. Her laboratory data and histological findings satisfied the criteria for autoimmune hepatitis (AIH) as revised by the International AIH Group. Laboratory examinations (indirect immunofluorescence and immunoblotting analyses) revealed that anti-Golgi complex antibodies (AGA) were positive in her serum. AGA are thought to be closely associated with AIH and/or liver dysfunction according to several reports.
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