Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pigmentation01:19

Pigmentation

3.8K
The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
3.8K
Acne Infection01:27

Acne Infection

94
Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
94
Mutations01:35

Mutations

31.2K
Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
31.2K
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

3.6K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
3.6K
Skin Cancer01:30

Skin Cancer

5.2K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.2K
Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

8.1K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
8.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exploring the optimal factor structure of mind-wandering: Associations with neuroticism.

PloS one·2024
Same author

A parallel-arm, randomized trial of Behavioral Activation Therapy for anhedonia versus mindfulness-based cognitive therapy for adults with anhedonia.

Behaviour research and therapy·2024
Same author

Ecthyma gangrenosum due to Pseudomonas fluorescens.

Cutis·2018
Same author

Antiphospholipid syndrome in a patient with rheumatoid arthritis.

Cutis·2017
Same author

Risk of skin cancer in multiple myeloma patients: a retrospective cohort study.

European journal of haematology·2016
Same author

A dermatologist at heart: the Osler legacy at Johns Hopkins.

International journal of dermatology·2016

Related Experiment Video

Updated: May 4, 2026

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
12:37

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

Published on: September 7, 2013

17.8K

Update on tanning: More risks, fewer benefits.

Ryan E O'Leary1, Joseph Diehl1, Paul C Levins1

  • 1Department of Dermatology, David Geffen School of Medicine at University of California, Los Angeles, California.

Journal of the American Academy of Dermatology
|January 7, 2014
PubMed
Summary

This review examines the evolving science of skin tanning, covering its protective and cosmetic aspects, medical benefits, and risks associated with sun exposure and indoor tanning services.

Keywords:
indoor tanningmelanotanself-tannerssunscreentanning benefitstanning pillstanning risksα-melanocyte-stimulating hormone analogues

More Related Videos

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

38.4K
Studying Chronic Exposure of Mice to Ultraviolet B Radiation
03:20

Studying Chronic Exposure of Mice to Ultraviolet B Radiation

Published on: August 19, 2025

2.0K

Related Experiment Videos

Last Updated: May 4, 2026

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
12:37

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

Published on: September 7, 2013

17.8K
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

38.4K
Studying Chronic Exposure of Mice to Ultraviolet B Radiation
03:20

Studying Chronic Exposure of Mice to Ultraviolet B Radiation

Published on: August 19, 2025

2.0K

Area of Science:

  • Dermatology
  • Photobiology
  • Public Health

Background:

  • The tanning response, or increased skin pigmentation after UV exposure, involves protective, reparative, and cosmetic factors.
  • Current research explores tanning physiology, medical benefits, sunscreen efficacy, self-tanners, indoor tanning risks, and new hormone analogues.
  • High-risk tanning behaviors are rising, coinciding with increased melanoma incidence.

Purpose of the Study:

  • To review the multifaceted aspects of the tanning response.
  • To analyze the risks and benefits associated with various tanning methods.
  • To provide dermatologists with relevant information for advising young patients.

Main Methods:

  • Literature review of basic science, clinical research, and public health studies.
  • Analysis of physiological mechanisms, medical implications, and behavioral trends.
  • Focus on dermatological perspectives concerning adolescents and young adults.

Main Results:

  • Tanning involves complex physiological and protective mechanisms.
  • Both natural and artificial tanning methods present distinct risks and benefits.
  • Melanoma incidence is rising, particularly with increased high-risk tanning behaviors.

Conclusions:

  • Understanding the tanning response is crucial for public health and clinical dermatology.
  • Dermatologists play a key role in educating patients, especially young adults, about tanning risks.
  • Further research is needed to address the growing concerns surrounding tanning behaviors and skin cancer.