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Related Concept Videos

Blood Transfusion01:15

Blood Transfusion

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Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
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Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

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Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
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Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
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Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration01:25

Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration

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Hemoperfusion and hemofiltration are critical techniques in medical treatments to eliminate accumulated drugs, metabolites, and electrolytes from the bloodstream. These methods are particularly vital in cases of accidental poisoning and drug overdose.Hemoperfusion involves passing blood through an adsorbent material to remove unwanted substances. The main adsorbents used in hemoperfusion include activated charcoal and Amberlite resins. Activated charcoal can adsorb both polar and nonpolar...
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Blood Typing01:10

Blood Typing

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Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target...
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Blood Types02:20

Blood Types

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Human blood is classified into different types based on the presence of antigens on the red blood cell's surface and antibodies in the plasma. Proper identification of blood type is essential for successful blood transfusion. The International Society of Blood Transfusion has identified 38 human blood types based on the surface antigens on the red blood cells. The most common types are ABO, Rh, and MNS blood types.
ABO blood group
ABO antigens are glycoproteins encoded by genes present on...
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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
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The ONTraC Ontario program in blood conservation.

John Freedman1

  • 1Laboratory Medicine & Pathobiology, University of Toronto, St. Michael's Hospital, 30 Bond Street, Room 2-006, Shuter Wing, Toronto, Ontario M5B 1W8, Canada.

Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis
|January 7, 2014
PubMed
Summary

Patient Blood Management (PBM) significantly reduces blood transfusions and improves patient outcomes. The ONTraC program demonstrated PBM

Keywords:
Blood conservationONTraCPatient blood managementTransfusion rates

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Area of Science:

  • Transfusion Medicine
  • Healthcare Management
  • Patient Safety

Background:

  • Blood transfusion carries potential adverse effects.
  • Patient Blood Management (PBM) offers an alternative approach.
  • Minimizing unnecessary transfusions is crucial for patient care.

Purpose of the Study:

  • To evaluate the effectiveness of the ONTraC program in implementing Patient Blood Management (PBM).
  • To assess the impact of PBM on transfusion rates and clinical outcomes.
  • To determine the cost-effectiveness of the ONTraC PBM program.

Main Methods:

  • The ONTraC program involved transfusion coordinators across 25 Ontario hospitals.
  • Implementation of PBM strategies focused on reducing blood transfusions.
  • Data collected from program inception (2002) to 2011.

Main Results:

  • The ONTraC program achieved significant reductions in blood transfusion rates.
  • Improved clinical outcomes were observed in patients managed under the PBM program.
  • The PBM initiative proved to be highly cost-effective.

Conclusions:

  • Patient Blood Management (PBM) is a successful paradigm shift in transfusion practice.
  • The ONTraC program demonstrates the efficacy and cost-effectiveness of PBM.
  • Widespread adoption of PBM can enhance patient safety and optimize healthcare resources.