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Psychotic episode secondary to metronidazole use
Mili Khandheria1, Erica Snook1, Christopher Thomas1
1University of Texas Medical Branch, Galveston, TX 77555, USA.
Objective:
Psychosis is a recognized but often forgotten side effect of many commonly prescribed medications.
Method:
A case of psychosis in a 27-year-old female related to metronidazole treatment is presented along with review of possible mechanisms.
Results:
The onset and resolution of psychosis appeared to coincide with metronidazole treatment.
Conclusions:
Clinicians should be aware of medication-related psychosis.
Insights
Psychosis can be a side effect of common medications. A case study highlights psychosis linked to metronidazole, emphasizing the need for clinical awareness of drug-induced psychosis.
Area of Science:
- Neuroscience
- Pharmacology
- Psychiatry
Background:
- Psychosis is an uncommon but recognized adverse effect of various pharmaceutical agents.
- Medication-induced psychosis necessitates careful differential diagnosis.
Observation:
- A 27-year-old female patient developed psychosis during metronidazole therapy.
- The patient's psychotic symptoms emerged and resolved concurrently with metronidazole administration.
Findings:
- Metronidazole, an antibiotic, was temporally associated with the onset and cessation of psychotic symptoms.
- This case suggests a potential causal link between metronidazole and drug-induced psychosis.
Implications:
- Healthcare providers must consider medication side effects, including psychosis, in patient evaluations.
- Increased awareness of drug-induced psychosis is crucial for accurate diagnosis and management.
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