Psychotic episode secondary to metronidazole use

Mili Khandheria1, Erica Snook1, Christopher Thomas1

  • 1University of Texas Medical Branch, Galveston, TX 77555, USA.

Abstract

Insights

Psychosis can be a side effect of common medications. A case study highlights psychosis linked to metronidazole, emphasizing the need for clinical awareness of drug-induced psychosis.

Area of Science:

  • Neuroscience
  • Pharmacology
  • Psychiatry

Background:

  • Psychosis is an uncommon but recognized adverse effect of various pharmaceutical agents.
  • Medication-induced psychosis necessitates careful differential diagnosis.

Observation:

  • A 27-year-old female patient developed psychosis during metronidazole therapy.
  • The patient's psychotic symptoms emerged and resolved concurrently with metronidazole administration.

Findings:

  • Metronidazole, an antibiotic, was temporally associated with the onset and cessation of psychotic symptoms.
  • This case suggests a potential causal link between metronidazole and drug-induced psychosis.

Implications:

  • Healthcare providers must consider medication side effects, including psychosis, in patient evaluations.
  • Increased awareness of drug-induced psychosis is crucial for accurate diagnosis and management.

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