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Updated: May 4, 2026

A Simple Flow Cytometric Method to Measure Glucose Uptake and Glucose Transporter Expression for Monocyte Subpopulations in Whole Blood
Published on: August 12, 2016
Differential expression of monocyte surface markers among TB patients with diabetes co-morbidity
Samuel S Stew1, Perla J Martinez2, Larry S Schlesinger3
1UT Health Houston, School of Public Health at Brownsville, 80 Fort Brown, Brownsville, Texas 78520, USA; The Advisory Board Company, Austin, Texas, USA.
Abstract:
The expression of monocyte surface markers was compared between tuberculosis patients with and without type 2 diabetes (DM2). DM2 was associated with increased CCR2 expression, which may restrain monocyte traffic to the lung. Other host factors associated with baseline monocyte changes were older age (associated with lower CD11b) and obesity (associated with higher RAGE). Given that DM2 patients are more likely to be older and obese, their monocytes are predicted to be altered in function in ways that affect their interaction with Mycobacterium tuberculosis.
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