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Trinorditerpenes from the roots of Flueggea virosa
Chih-Hua Chao1, Ju-Chien Cheng2, Tsong-Long Hwang3
1School of Pharmacy, China Medical University, Taichung 404, Taiwan; Chinese Medicine Research and Development Center, China Medical University Hospital, Taichung 404, Taiwan.
Bioorganic & Medicinal Chemistry Letters
|January 7, 2014
Abstract:
Two trinorditerpenes, flueggrenes A and B (1 and 2), have been isolated from the roots of Flueggea virosa. Their structures were established by extensive analyses of spectroscopic data. The isolates were evaluated for anti-HCV activity, as well as the inhibition of superoxide anion generation and elastase release in response to FMLP/cytochalasin B.
