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Polyglutamine expansion disturbs the endoplasmic reticulum formation, leading to caspase-7 activation through Bax

Masashi Ueda1, Shimo Li1, Masanori Itoh1

  • 1Department of Neurobiology, Gifu University Graduate School of Medicine, Gifu, Japan.

Biochemical and Biophysical Research Communications
|January 7, 2014
PubMed

Keywords:
ApoptosisBcl-2 familyCaspaseEndoplasmic reticulumNeurodegenerationPolyglutamine expansion disorder

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