Biofabrication of silver nanoparticles using Andrographis paniculata.

Area of Science:

• Green Chemistry
• Nanotechnology
• Mycology

Background:

• The development of novel strategies for synthesizing silver nanoparticles (AgNPs) is an active area of research.
• Plant extracts offer an economical, cost-effective, and environmentally friendly alternative for nanoparticle synthesis.
• Andrographis paniculata is explored as a biological source for AgNP fabrication.

Purpose of the Study:

• To biofabricate silver nanoparticles (AgNPs) using Andrographis paniculata extract.
• To characterize the synthesized AgNPs using various spectroscopic and microscopic techniques.
• To evaluate the antifungal efficacy of the as-synthesized AgNPs.

Main Methods:

• Biofabrication of AgNPs using Andrographis paniculata extract.
• Characterization using UV-Vis spectroscopy, SEM-EDX, XRD, and FT-IR.
• Analysis of size and stability via Nanoparticle analyzer.
• Antifungal activity testing.

Main Results:

• UV-Vis spectroscopy confirmed the synthesis of AgNPs.
• SEM, EDX, and XRD analyses verified the morphology and crystalline nature of AgNPs.
• The average size of AgNPs was determined to be 54 ± 2 nm.
• Zeta potential of -50.7 mV indicated good stability.
• The synthesized AgNPs demonstrated potent antifungal activity.

Conclusions:

• Andrographis paniculata facilitates the green synthesis of stable silver nanoparticles.
• The synthesized AgNPs possess significant antifungal properties, suggesting potential applications in controlling fungal infections.