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Related Concept Videos

Upper GI Series: Barium Swallow01:24

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The Barium Swallow Study, or a Barium Esophagogram, is a diagnostic imaging method used to visualize the upper gastrointestinal (GI) tract, including the esophagus, stomach, and small intestine. It employs barium sulfate, a radiopaque contrast material, to provide clear images of the upper digestive system, helping to identify abnormalities, diseases, or structural issues.
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A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...
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Esophageal achalasia is a chronic neurogenic disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent or ineffective peristalsis in the distal esophagus. This leads to a functional obstruction without a physical blockage, despite significant disruption of esophageal motility.EtiologyAchalasia is caused by degeneration of the myenteric (Auerbach's) plexus, specifically the loss of inhibitory ganglion cells that produce vasoactive intestinal peptide...
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Vomiting is a complex physiological response to expel harmful or irritating substances from the body. It's a defensive mechanism triggered by stimuli like poisons, microbial toxins, cytotoxic drugs, and mechanical abdominal distension. The process is centrally coordinated by the vomiting (or emetic) center located in the medulla of the brainstem. This area, rich in muscarinic M1, histamine H1, neurokinin 1 (NK1), and serotonin 5-HT3 receptors, coordinates the act of vomiting through...
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Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
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Hemorrhagic Stroke l: Introduction01:17

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A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
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Related Experiment Video

Updated: May 4, 2026

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
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A case of swallow syncope.

Peter K Moore1, Jenny K Lee1, Joel A Garcia1

  • 1Cardiology Division, Department of Medicine, Denver Health Medical Center, Denver, Colorado 80204.

Texas Heart Institute Journal
|January 7, 2014
PubMed
Summary
This summary is machine-generated.

Swallow syncope, a rare disorder triggered by eating, can cause dangerous heart block. A pacemaker successfully treated a patient experiencing this rare condition, highlighting an exaggerated reflex as the cause.

Keywords:
Deglutition/physiologydeglutition disorderseating/physiologyheart block/complications/diagnosis/physiopathologysyncope, vasovagal/diagnosis/etiology/therapytreatment outcome

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Area of Science:

  • Cardiology
  • Neurology

Background:

  • Swallow syncope (deglutition syncope) is a rare condition triggered by eating.
  • It is often associated with esophageal or structural heart disease.
  • Conservative management by eliminating predisposing factors is sometimes effective.

Observation:

  • A 65-year-old woman, with no prior heart or esophageal issues, experienced syncope while driving and eating after a motor vehicle accident.
  • During hospitalization, she lost consciousness while eating solid food.
  • Continuous electrocardiographic monitoring revealed complete heart block without ventricular escape.

Findings:

  • The patient experienced asystole, a complete cessation of heart electrical activity, during deglutition.
  • This was attributed to an exaggerated vago-glossopharyngeal reflex.
  • A dual-chamber permanent pacemaker was implanted.

Implications:

  • This case demonstrates a severe presentation of swallow syncope.
  • Pacemaker implantation effectively resolved symptoms in this patient.
  • It underscores the importance of considering neurological reflexes in unexplained syncope.