Diagnosis of pediatric nasopharynx carcinoma after recurrent adenoidectomy

Koray Cengiz1, Tolgar Lütfi Kumral2, Güven Yıldırım2

  • 1Department of Otorhinolaryngology-Head and Neck Surgery, Private Gazi Hospital, Sultangazi, Istanbul 34260, Turkey.

Insights

Nasopharyngeal carcinoma (NPC) is rare in children but can mimic adenoid hypertrophy. Surgeons must remain vigilant for suspicious signs during routine adenoidectomy to ensure timely diagnosis of this advanced disease.

Area of Science:

  • Otolaryngology
  • Pediatric Oncology
  • Surgical Pathology

Background:

  • Nasopharyngeal soft tissue masses in children are most commonly due to adenoid hypertrophy.
  • Nasopharyngeal carcinoma (NPC), though rare in pediatric populations, presents significant diagnostic challenges.
  • Common symptoms like nasal obstruction and otitis media often lead to advanced NPC diagnosis.

Purpose of the Study:

  • To report a case of pediatric nasopharyngeal carcinoma initially presenting as recurrent adenoid hypertrophy.
  • To highlight the importance of considering NPC in the differential diagnosis of persistent nasal obstruction in children.
  • To emphasize surgeon awareness of subtle signs during routine procedures.

Main Methods:

  • Case report of a 7-year-old boy undergoing recurrent adenoidectomy.
  • Intraoperative suspicion of a hard nasopharyngeal mass.
  • Histopathological diagnosis of nasopharyngeal carcinoma.

Main Results:

  • The patient presented with recurrent nasal obstruction necessitating repeat adenoidectomy.
  • A hard mass was discovered during the second operation, leading to NPC diagnosis.
  • NPC diagnosis occurred at an advanced stage due to initial presentation mimicking benign conditions.

Conclusions:

  • Adenoidectomy is a common procedure where NPC is an unlikely consideration.
  • Surgeons must be alert to specific signs and symptoms that warrant suspicion for NPC.
  • Early detection of pediatric NPC is crucial, despite its rarity and challenging presentation.