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High Sensitivity Measurement of Transcription Factor-DNA Binding Affinities by Competitive Titration Using Fluorescence Microscopy
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Multiple-binding-site mechanism explains concentration-dependent unbinding rates of DNA-binding proteins

Charles E Sing1, Monica Olvera de la Cruz, John F Marko

  • 1Department of Materials Science, Northwestern University, 2220 Cook Dr. Evanston, IL 60208, USA, Department of Molecular Biosciences, Northwestern University, Evanston, IL 60208, USA and Department of Physics and Astronomy, Northwestern University, Evanston, IL 60208, USA.

Nucleic Acids Research
|January 8, 2014
PubMed

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