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Updated: May 4, 2026

Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial
Published on: August 19, 2025
[Successful treatment of multiple breast tumors with breast-conserving surgery]
Saki Nagashima1, Kenichi Sakurai, Shuhei Suzuki
1Division of Breast and Endocrine Surgery, Dept. of Surgery, Nihon University School of Medicine.
Abstract:
We report a case in which we were able to treat multiple tumors in the right breast with breast-conserving surgery. The patient was a 60-year-old woman in whom mammography revealed grouped round calcifications and distortion in the right breast. The tumor was not palpable. Ultrasonography revealed 3 tumors in the patient's right breast. One tumor, 14.5 mm in diameter, was located in the AC area of her right breast. Vacuum-assisted core-needle biopsy was performed on this tumor, and histopathological examination revealed invasive ductal carcinoma of the breast. The tumor was estrogen receptor (ER)-positive, progesterone receptor( PgR)-negative, and human epidermal growth factor receptor( HER)-2-positive. Another tumor, 5.5 mm in diameter, was located in the C area of the patient's right breast. This tumor was diagnosed as a satellite lesion of the tumor in the AC area. The third tumor, 19.0 mm in diameter, was located in the A area of the patient's right breast. This tumor was expected to be a fibroadenoma on the basis of the clinical findings. We performed breast-conserving surgery to remove these 3 tumors and biopsied the sentinel lymph nodes. Intra-operative rapid pathological diagnosis indicated that the surgical margins were negative and the sentinel lymph nodes were negative for metastasis. The final pathological diagnosis was the same as the preoperative diagnosis.
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