Related Experiment Video
Updated: May 4, 2026

07:56
Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
Published on: January 29, 2018
17.5K
Bone densitometry: relevance to health care
1Associate Professor of Medicine, Department Endocrinology, Austin Hospital, Heidelberg 3084; University of Melbourne, Melbourne, Australia.
Asia Pacific Journal of Clinical Nutrition
|January 8, 2014
Summary
Bone densitometry is crucial for assessing fracture risk, especially in individuals with low bone density. Screening may benefit women considering hormone replacement therapy (HRT), but population-wide efficacy requires further study.
Area of Science:
- Osteoporosis Research
- Bone Health Assessment
- Geriatric Medicine
Background:
- Low bone density significantly increases fracture risk.
- Bone densitometry is a key tool for evaluating fracture risk and monitoring treatment efficacy.
- Most fractures occur in individuals with below-average bone density.
Purpose of the Study:
- To elucidate the relevance of bone densitometry in healthcare.
- To assess the quantitative estimation of fracture risk using bone densitometry.
- To evaluate the utility of bone densitometry in response to aging, disease, or medical treatment.
Main Methods:
- Review of existing literature on bone densitometry and fracture risk.
- Discussion of challenges in population-wide screening efficacy.
- Identification of specific populations that may benefit from screening.
Main Results:
- Bone densitometry provides a quantitative measure of fracture risk.
- Most fracture patients fall into lower bone density quartiles.
- Screening is particularly recommended for women considering hormone replacement therapy (HRT).
Conclusions:
- Bone densitometry is essential for personalized fracture risk assessment.
- Further research is needed on bone quality, pathogenesis of low bone density, and factors contributing to bone density.
- Population-wide screening efficacy and treatment success require additional investigation.
More Related Videos
Related Concept Videos
Bone Disorders
8.0K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
8.0K
Bone Remodeling
34.4K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
34.4K
Essential Minerals for Bone Health
6.2K
The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
6.2K
Role of Vitamins in Maintaining Bone Health
5.1K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
5.1K
Skeleton and Calcium Homeostasis
8.4K
Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
8.4K
Osteoclasts in Bone Remodeling
3.9K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
3.9K

