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Updated: May 4, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Published on: June 12, 2021
An update on mechanical circulatory support for heart failure therapy
Hadi Daood Toeg1, Talal Al-Atassi, Jose Perez Garcia
1aDivision of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, Ontario, Canada bDivision of Cardiac Surgery, Harvard University, Massachusetts General Hospital, Boston, Massachusetts, USA.
Mechanical circulatory support (MCS) offers a promising treatment for advanced heart failure. Newer continuous flow left ventricular assist devices (LVADs) show improved durability and survival, making them a viable option for destination therapy.
Area of Science:
- Cardiology
- Biomedical Engineering
Background:
- Refractory heart failure necessitates advanced treatment options.
- Mechanical circulatory support (MCS) has evolved significantly over time.
Purpose of the Study:
- To review current studies on MCS for heart failure.
- To explore future mechanical treatment alternatives.
Main Methods:
- Review of contemporary studies utilizing MCS.
- Analysis of advancements in mechanical assist devices.
Main Results:
- Early MCS devices had high adverse event rates.
- Modern continuous flow left ventricular assist devices (LVADs) demonstrate improved durability and reduced morbidity.
- Increased use of LVADs for destination therapy is observed.
Conclusions:
- Second and third-generation continuous flow LVADs offer enhanced durability and survival.
- MCS is becoming a primary treatment for refractory heart failure.
- Future developments aim for less invasive, smaller, and more efficient MCS devices.
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