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Tissue Engineering: Construction of a Multicellular 3D Scaffold for the Delivery of Layered Cell Sheets
Published on: October 3, 2014
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Engineered micro-objects as scaffolding elements in cellular building blocks for bottom-up tissue engineering
A Leferink1, D Schipper, E Arts
1Department of Tissue Regeneration, MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente, 7522, NB, Enschede, The Netherlands.
Advanced Materials (Deerfield Beach, Fla.)
|January 8, 2014
Abstract:
A material-based bottom-up approach is proposed towards an assembly of cells and engineered micro-objects at the macroscale. We show how shape, size and wettability of engineered micro-objects play an important role in the behavior of cells on these objects. This approach can, among other applications, be used as a tool to engineer complex 3D tissues of clinically relevant size.
