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Updated: May 4, 2026
09:06
MicroRNA Amplification and Recognition through Locked-nucleic-acid In situ Hybridization as a Novel Detection and Quantification Method
Published on: October 7, 2025
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MicroRNAs - a new generation molecular targets for treating cellular diseases
1Molecular Imaging Program at Stanford, Bio-X Program, Department of Radiology, Stanford University School of Medicine, Stanford, California, USA.
Theranostics
|January 8, 2014
Summary
MicroRNAs (miRNAs) regulate gene expression and are crucial therapeutic targets for cancer and other diseases. This issue explores miRNA
Area of Science:
- Molecular Biology
- Genetics
- Biochemistry
Background:
- MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression post-transcriptionally.
- Dysregulation of miRNA expression is implicated in various cellular pathologies, notably cancer.
- miRNAs play critical roles in maintaining cellular homeostasis and function.
Discussion:
- This special issue focuses on the therapeutic potential of miRNAs in cancer and other cellular diseases.
- It examines the challenges and strategies for effective miRNA delivery for therapeutic applications.
- The role of molecular imaging in monitoring miRNA delivery in vivo is also discussed.
Key Insights:
- miRNAs are vital regulators of gene expression with significant therapeutic implications.
- Targeting miRNAs offers a promising strategy for treating diseases like cancer.
- Overcoming delivery obstacles is key to realizing the clinical potential of miRNA therapeutics.
Outlook:
- Future research should focus on optimizing miRNA delivery systems for enhanced efficacy and safety.
- Non-invasive monitoring of therapeutic miRNAs using molecular imaging will be crucial for clinical translation.
- Exploring miRNAs as biomarkers and therapeutic agents holds promise for personalized medicine.
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