[Progress of Masquelet technique to repair bone defect].

Area of Science:

• Orthopedic Surgery
• Regenerative Medicine
• Biomaterials

Context:

• Bone defects pose significant challenges in orthopedic surgery.
• Current repair methods often have limitations in efficacy and application.
• The Masquelet technique offers a novel approach to bone defect reconstruction.

Purpose:

• To review and summarize the advancements and applications of the Masquelet technique for bone defect repair.
• To highlight the biological mechanisms and clinical outcomes associated with this technique.

Summary:

• The Masquelet technique is a two-step procedure involving a bone cement spacer to create an induced membrane, followed by cancellous bone grafting.
• The induced membrane is vascularized and rich in osteoinductive factors, promoting new bone formation.
• Clinical applications demonstrate success in various bone defect types, including large defects up to 25 cm.

Impact:

• The Masquelet technique provides a reliable, easy-to-operate, and versatile solution for bone defect repair.
• It offers advantages over traditional methods with fewer complications and wider applicability.
• This technique is particularly effective for defects resulting from infection or tumor resection.