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Related Experiment Video

Updated: May 4, 2026

Immunostaining for DNA Modifications: Computational Analysis of Confocal Images
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A context dependent role for DNA methylation in bivalves.

Mackenzie R Gavery, Steven B Roberts

    Briefings in Functional Genomics
    |January 9, 2014
    PubMed
    Summary

    DNA methylation in bivalves is mainly in gene bodies, and its function is unclear. This review explores its evolutionary and ecological roles, possibly linked to gene function and life history traits.

    Area of Science:

    • Marine Biology
    • Genomics
    • Epigenetics

    Background:

    • DNA methylation patterns in bivalves are distinct, with limited methylation predominantly located in gene bodies.
    • The functional significance of this gene body DNA methylation in bivalves is not well understood.
    • Existing hypotheses suggest a link between DNA methylation, gene function, and lineage-specific adaptations.

    Purpose of the Study:

    • To review current knowledge on DNA methylation in bivalve species.
    • To explore the potential evolutionary and ecological roles of gene body DNA methylation in bivalves.
    • To investigate how DNA methylation might influence phenotypic plasticity and genome regulation.

    Main Methods:

    • Literature review of existing studies on bivalve DNA methylation.
    Keywords:
    bivalvesepigeneticsinvertebratesmethylationoystersplasticity

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  • Analysis of current hypotheses regarding gene body methylation function.
  • Exploration of evolutionary and ecological contexts for DNA methylation.

    • Main Results:

    • Limited DNA methylation in bivalves is primarily found in gene bodies.
    • Absence of DNA methylation may promote transcriptional plasticity and transposable element activity in certain genes.
    • DNA methylation might be involved in targeted genome regulation for essential gene functions.

    Conclusions:

    • The role of gene body DNA methylation in bivalves is likely context-dependent, influenced by gene function.
    • DNA methylation may play a role in adapting to lineage-specific life history traits.
    • Further research is needed to fully elucidate the evolutionary and ecological significance of DNA methylation in bivalves.