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Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions
Published on: July 17, 2020
Novel prenylated bichalcone and chalcone from Humulus lupulus and their quinone reductase induction activities
Liyan Yu1, Fuxian Zhang2, Zhijuan Hu1
1Institute of Marine Biology & Natural Products, Ocean College, Zhejiang University, No. 866 Yuhangtang Rd., Hangzhou 310058, China.
Abstract:
A new prenylated chalcone xanthohumol M (1), a novel prenylated bichalcone humulusol (2) and six known chalcones (3-8) were found from Humulus lupulus. Their structures were determined by spectroscopic methods. All the chalcones' electrophilic abilities were assessed by GSH (glutathione) rapid screening, and their QR (quinone reductase) induction activities were evaluated using hepa 1c1c7 cells. The results of electrophilic assay and QR induction activity assay were quite well. New compounds 1 and 2, along with some known prenylated chalcones, displayed certain QR induction activity.
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