Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

8.5K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
8.5K
Diabetic Retinopathy01:27

Diabetic Retinopathy

55
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
55
Regulated Protein Degradation02:58

Regulated Protein Degradation

6.6K
It is vital to regulate the activity of enzymatic as well as non-enzymatic proteins inside the cell. This can be achieved either through creating a balance between their rate of synthesis and degradation or regulating the intrinsic activity of the protein. Both these regulation mechanisms play an essential role in the normal functioning of cells.
Protein degradation plays two important roles in the cells. It helps to protect cells from misfolded or damaged proteins before they lead to a...
6.6K
Microbiome of the Eye01:22

Microbiome of the Eye

67
The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
67
Degenerative Disc Disease I: Introduction01:27

Degenerative Disc Disease I: Introduction

29
Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
29
Accessory Structures of the Eye01:17

Accessory Structures of the Eye

4.3K
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
4.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Urinary sodium and potassium in a sample of healthy adults in Sydney, Australia.

Asia Pacific journal of clinical nutrition·2013
Same author

Coronary heart disease epidemics: not all the same.

Heart (British Cardiac Society)·2008
Same author

Empowering family doctors and patients in nutrition communication.

European journal of clinical nutrition·2005
Same author

Some problems with Cochrane reviews of diet and chronic disease.

European journal of clinical nutrition·2005
Same author

The A2 milk case: a critical review.

European journal of clinical nutrition·2005
Same author

Lifting the profile of nutrition in Australia.

Asia Pacific journal of clinical nutrition·2003

Related Experiment Video

Updated: May 4, 2026

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

4.1K

Nutrients and degenerative eye diseases.

A S Truswell1, P Mitchell

  • 1Human Nutrition Unit, Biochemistry Department, University of Sydney and Australia.

Asia Pacific Journal of Clinical Nutrition
|January 9, 2014
PubMed
Summary

Antioxidant nutrients like vitamin C, vitamin E, and carotenoids show promise in preventing cataracts, a common age-related eye condition. Further research, including controlled trials, is needed to confirm their protective effects against age-related macular degeneration.

More Related Videos

Determination of Mitochondrial Respiration and Glycolysis in Ex Vivo Retinal Tissue Samples
08:45

Determination of Mitochondrial Respiration and Glycolysis in Ex Vivo Retinal Tissue Samples

Published on: August 4, 2021

4.3K
In Vivo Dynamics of Retinal Microglial Activation During Neurodegeneration: Confocal Ophthalmoscopic Imaging and Cell Morphometry in Mouse Glaucoma
12:48

In Vivo Dynamics of Retinal Microglial Activation During Neurodegeneration: Confocal Ophthalmoscopic Imaging and Cell Morphometry in Mouse Glaucoma

Published on: May 11, 2015

10.4K

Related Experiment Videos

Last Updated: May 4, 2026

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

4.1K
Determination of Mitochondrial Respiration and Glycolysis in Ex Vivo Retinal Tissue Samples
08:45

Determination of Mitochondrial Respiration and Glycolysis in Ex Vivo Retinal Tissue Samples

Published on: August 4, 2021

4.3K
In Vivo Dynamics of Retinal Microglial Activation During Neurodegeneration: Confocal Ophthalmoscopic Imaging and Cell Morphometry in Mouse Glaucoma
12:48

In Vivo Dynamics of Retinal Microglial Activation During Neurodegeneration: Confocal Ophthalmoscopic Imaging and Cell Morphometry in Mouse Glaucoma

Published on: May 11, 2015

10.4K

Area of Science:

  • Ophthalmology
  • Nutritional Science
  • Gerontology

Background:

  • Cataracts and age-related macular degeneration (AMD) are leading causes of vision loss in the elderly.
  • Both conditions are suspected to result from photo-oxidative damage.
  • The eye possesses high concentrations of antioxidants like vitamin C and zinc, suggesting a role in protection.

Purpose of the Study:

  • To review existing evidence on the role of antioxidant nutrients in preventing age-related eye diseases.
  • To assess the potential benefits of vitamin C, vitamin E, and carotenoids for cataract and AMD.
  • To determine the need for further clinical trials and observational studies.

Main Methods:

  • Review of five case-control studies and two prospective studies on cataracts and nutrient intake.
  • Analysis of dietary histories and blood levels for vitamin estimation.
  • Examination of existing literature on vitamin E deficiency and retinal degeneration.

Main Results:

  • Five out of six studies indicated a protective effect of vitamin C against cataracts.
  • Vitamin E and carotenoids appeared protective in 5 out of 7 studies for cataracts.
  • No clear nutrient-disease relationship has emerged for AMD from limited human studies.

Conclusions:

  • Controlled trials of antioxidant nutrients for cataract prevention are warranted.
  • Current use of antioxidant supplements for AMD is ahead of scientific evidence.
  • More observational studies are needed for AMD, with a large intervention study (AREDS) planned.