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Measurement of Tactile Allodynia in a Murine Model of Bacterial Prostatitis
Published on: January 16, 2013
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Chronic bacterial prostatitis in men with spinal cord injury
Jörg Krebs1, Peter Bartel, Jürgen Pannek
1Clinical Trial Unit, Swiss Paraplegic Centre, Nottwil, Switzerland.
World Journal of Urology
|January 9, 2014
Summary
Most men with spinal cord injury (SCI) have asymptomatic bacterial prostatitis. However, this condition does not significantly contribute to recurrent urinary tract infections (UTI) in SCI patients.
Area of Science:
- Urology
- Infectious Diseases
- Neurology
Background:
- Recurrent urinary tract infections (UTI) pose a significant challenge for individuals with spinal cord injury (SCI).
- Chronic bacterial prostatitis is a potential, yet unconfirmed, source of recurrent UTIs in this population.
Purpose of the Study:
- To investigate the prevalence of chronic bacterial prostatitis in men with SCI.
- To determine the role of chronic bacterial prostatitis in the development of recurrent symptomatic UTIs among SCI men.
Main Methods:
- Prospective, cross-sectional study at a single SCI rehabilitation center.
- Urine samples collected before and after prostate massage for microbiological analysis and white blood cell counts in 50 men with chronic SCI.
- Retrospective collection of patient characteristics, bladder voiding data, and UTI history.
Main Results:
- The majority of participants (78%) had pathogenic bacteria in post-massage urine samples, often also present pre-massage.
- No significant association was found between positive post-massage urine cultures and the number of symptomatic UTIs.
- The prevalence of positive cultures did not differ between men with recurrent and sporadic UTIs.
Conclusions:
- Asymptomatic bacterial prostatitis is common in men with SCI.
- Bacterial prostatitis is not a primary driver of recurrent UTIs in SCI patients.
- The necessity of antibiotic treatment for asymptomatic bacterial prostatitis in SCI men with recurrent UTIs warrants further consideration.
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