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Updated: May 4, 2026

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Percutaneous coronary intervention in a 3-year-old with hypoplastic left heart syndrome
P M E Noonan1, D Taliotis1, A Alahmar1
1East Midlands Congenital Heart Centre Glenfield Hospital, Groby Road, Leicester LE3 9QP.
Insights
This case report highlights a rare myocardial infarction in a child with hypoplastic left heart syndrome (HLHS). Thrombus aspiration successfully treated the coronary artery occlusion, improving clinical response.
Area of Science:
- Pediatric Cardiology
- Congenital Heart Disease
- Interventional Cardiology
Background:
- Surgical palliation for hypoplastic left heart syndrome (HLHS) has improved, but interstage mortality remains a challenge.
- Predicting and preventing interstage mortality in HLHS patients is crucial for better outcomes.
Observation:
- A 3-year-old boy with HLHS, palliated with a Glenn shunt, presented with acute myocardial infarction.
- The infarction was caused by near-total occlusion of the distal right coronary artery.
Findings:
- The patient was successfully treated with thrombus aspiration, showing a good clinical response.
- This is the first reported case of thrombus aspiration in complex pediatric congenital heart disease.
Implications:
- Thrombus aspiration can be an effective treatment for acute coronary artery occlusion in pediatric congenital heart disease.
- Collaboration between congenital and adult cardiologists is valuable for managing complex pediatric cardiac cases.
Abstract:
Mortality outcomes associated with surgical palliation for hypoplastic left heart syndrome (HLHS) have continued to improve with time. Despite these advances, interstage mortality continues to be difficult to predict and prevent. This case report details a 3-year-old boy with HLHS palliated with a Glenn shunt who presented with acute myocardial infarction due to near total occlusion of the distal right coronary artery. He was treated by thrombus aspiration with good clinical response. This is the first report of thrombus aspiration in complex pediatric congenital heart disease and demonstrates the utility of collaboration between congenital and adult cardiologists.
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