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Related Experiment Video

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Assessment of Physical Activity Intensity with Accelerometers and Oxygen Consumption
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The Oxford Participation and Activities Questionnaire: study protocol.

David Morley1, Sarah Dummett1, Laura Kelly1

  • 1Nuffield Department of Population Health, University of Oxford, Oxford, UK.

Patient Related Outcome Measures
|January 9, 2014
PubMed
Summary

A new patient-reported outcome measure (PROM), the Oxford Participation and Activities Questionnaire (Ox-PAQ), is being developed to assess activity and participation. This validated instrument aims to meet regulatory standards for use in clinical trials and intervention evaluations.

Keywords:
activityparticipationpatient-reported outcome measurequestionnaire

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Area of Science:

  • Health Sciences
  • Rehabilitation Medicine
  • Patient-Reported Outcome Measures

Background:

  • Growing emphasis on managing long-term conditions and maintaining patient activity.
  • Need for validated instruments to assess participation and activity in diverse health conditions.
  • Current measures often focus on disability and rehabilitation, lacking generic applicability and regulatory compliance.

Purpose of the Study:

  • To develop and validate a new patient-reported outcome measure (PROM) for assessing participation and activity.
  • To create the Oxford Participation and Activities Questionnaire (Ox-PAQ) aligned with regulatory standards.
  • To provide a generic instrument for evaluating interventions and use in clinical trials.

Main Methods:

  • Grounded in the WHO International Classification of Functioning, Disability, and Health framework.
  • Stakeholder engagement from project inception.
  • Item generation via patient interviews, cognitive interviews, focus groups, and postal surveys.
  • Statistical analyses including factor analysis, Rasch analysis, Cronbach's alpha, and item-total correlations.
  • Validation through large-scale surveys assessing health status, test-retest reliability, and responsiveness.

Main Results:

  • Development protocol for the Oxford Participation and Activities Questionnaire (Ox-PAQ) detailed.
  • Methodology ensures alignment with current regulatory standards and best practices for PROM development.
  • The Ox-PAQ is designed for broad applicability across various health conditions.

Conclusions:

  • The Oxford Participation and Activities Questionnaire (Ox-PAQ) development is timely given the focus on patient activity and participation.
  • The instrument has potential for significant uptake in clinical research and intervention evaluation.
  • Ox-PAQ aims to fill the gap for a validated, generic measure of participation and activity meeting regulatory requirements.