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Updated: May 4, 2026

Protein Film Infrared Electrochemistry Demonstrated for Study of H2 Oxidation by a [NiFe] Hydrogenase
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Published on: December 4, 2017

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H2O2-dependent substrate oxidation by an engineered diiron site in a bacterial hemerythrin

Yasunori Okamoto1, Akira Onoda, Hiroshi Sugimoto

  • 1Department of Applied Chemistry, Graduate School of Engineering, Osaka University, Suita, Osaka 565-0871, Japan. onoda@chem.eng.osaka-u.ac.jp thayashi@chem.eng.osaka-u.ac.jp.

Chemical Communications (Cambridge, England)
|January 9, 2014
PubMed
Summary

Researchers engineered a diiron site in DcrH-Hr to oxidize external substrates using hydrogen peroxide (H2O2). The modified enzyme successfully oxidized guaiacol and 1,4-cyclohexadiene, demonstrating a new catalytic capability.

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