Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Prostatic disorders: MR imaging at 1.5 T.

M E Phillips, H Y Kressel, C E Spritzer

    Radiology
    |August 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Urinary symptoms: broadening the horizons for the copeptin assay.

    Journal of endocrinological investigation·2019
    Same author

    Nocturia: current concepts and future perspectives.

    Acta physiologica (Oxford, England)·2012
    Same author

    Sympathetic innervation and chemical sympathectomy of canine bladder.

    Urology·2011
    Same author

    Does race affect postoperative outcomes in patients with low-risk prostate cancer who undergo radical prostatectomy?

    Urology·2008
    Same author

    Radiofrequency ablation of small renal cell carcinomas using multitined expandable electrodes: preliminary experience.

    Journal of vascular and interventional radiology : JVIR·2006
    Same author

    Transitional cell carcinoma of the fossa navicularis in a man with preexisting adenocarcinoma of the prostate.

    Urologia internationalis·2006
    Same journal

    Erratum for: Prediction of Lobar Emphysema Progression with a CT-Based Foundational Model.

    Radiology·2026
    Same journal

    Erratum for: Associations of MRI-derived Paraspinal IMAT and LMM with Cardiometabolic Risk Factors: Results from a German Cohort.

    Radiology·2026
    Same journal

    Erratum for: Blue Rubber Bleb Nevus Syndrome.

    Radiology·2026
    Same journal

    Redefining the Clinical Role of MRI in Endometrial Cancer Staging.

    Radiology·2026
    Same journal

    To Ablate or Not to Ablate: The Colorectal Liver Metastasis Question.

    Radiology·2026
    Same journal

    The Limits of Radiologic Categorization in Pulmonary Nonsolid Nodules.

    Radiology·2026
    See all related articles

    Magnetic resonance imaging (MRI) can identify extracapsular prostate cancer spread. A specific peripheral zone defect on MRI scans shows promise for detecting cancer extension, aiding in diagnosis.

    Area of Science:

    • Radiology
    • Oncology
    • Urology

    Background:

    • Accurate staging of prostate cancer is crucial for treatment planning.
    • Distinguishing between intracapsular and extracapsular disease impacts patient management.
    • Magnetic resonance imaging (MRI) offers detailed visualization of pelvic anatomy.

    Purpose of the Study:

    • To evaluate the utility of pelvic MRI in differentiating intracapsular from extracapsular prostate cancer.
    • To assess the ability of MRI to detect extracapsular extension (ECE) of prostate cancer.

    Main Methods:

    • Retrospective review of pelvic MRI scans (1.5 T) from 31 men with known genitourinary disease.
    • Analysis of axial images with long repetition times/echo times (TRs/TEs) to visualize prostatic zones.
    • Correlation of imaging findings with clinical and pathological data.

    Related Experiment Videos

    Main Results:

    • A peripheral zone defect (≥1 cm, ill-defined borders, lower signal intensity) was observed in all patients with known extracapsular prostate cancer.
    • This defect demonstrated 100% sensitivity but 54% specificity for detecting ECE, with excellent interobserver agreement.
    • Early-stage prostate cancer (Stage A2, B1) and benign prostatic hyperplasia (BPH) were not reliably detected or differentiated by MRI signal intensity alone.

    Conclusions:

    • Pelvic MRI, specifically the identification of a peripheral zone defect, shows high sensitivity for detecting extracapsular spread of prostate cancer.
    • MRI may play a role in differentiating intracapsular from extracapsular prostate carcinoma, potentially improving staging accuracy.
    • Further research is needed to improve the specificity of MRI in detecting ECE and to evaluate its role in detecting earlier stages of prostate cancer.