Mitral valve replacement in a patient with sickle cell anaemia

Cardiopulmonary bypass can be expected to cause problems in a patient with sickle cell anaemia (SCA) as such surgery is associated with various factors which may induce sickling and subsequent sickle cell crisis. This patient is only the second with SCA to have valve replacement performed, and is the seventh case reported in the English literature to have cardiopulmonary bypass surgery.