[Treatment of ectopic ventricular activity with palpitin (disopyramide)]

The therapeutic effect of palpitin (Gedeon Richter) was examined in an open clinical experiment with 30 patients with ectopic ventricular activity. The mean number of ventricular extra-systoles, established for one hour, was reduced from 573.7 to 149.7(p less than 0.001)--in 30.0% of the treated it completely disappeared, in 56.7% it was reduced with more than 50% and in 13.3%--there was no effect. The adverse effects are often (33.3%) but light, rarely necessitating the discontinuation of the treatment.