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USB-driven microfluidic chips on printed circuit boards.

Jiang Li1, Yixuan Wang, Enkai Dong

  • 1School of Mechanical Engineering, University of Science and Technology Beijing, Beijing 100083, China. lijiang@ustb.edu.cn.

Lab on a Chip
|January 10, 2014
PubMed
Summary
This summary is machine-generated.

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A new microfluidic chip integrates microchannels and sensors onto a printed circuit board for droplet generation and size detection. This technology enhances microfluidic integration into micro electrical-mechanical systems (MEMS).

Area of Science:

  • Microfluidics
  • Printed Circuit Board Technology
  • MEMS Technology

Background:

  • Microfluidic chips are essential for lab-on-a-chip applications.
  • Integrating microfluidics with electronics presents fabrication challenges.
  • Existing methods often require complex assembly and multiple substrates.

Purpose of the Study:

  • To present a novel technology for fabricating integrated microfluidic chips on printed circuit boards.
  • To demonstrate the chip's capability in generating and detecting emulsion droplets.
  • To highlight the improved integration potential for micro electrical-mechanical systems (MEMS).

Main Methods:

  • Fabrication of a microfluidic chip with integrated microchannels and microelectrodes directly on a copper-clad printed circuit board.

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Last Updated: May 4, 2026

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  • Demonstration of oil-in-water and water-in-oil emulsion droplet generation.
  • Utilizing USB interface for chip operation and downstream microelectrodes for droplet size detection.

    • Main Results:

    • Successful fabrication of a microfluidic chip with direct integration of channels and electrodes on a single substrate.
    • Demonstrated generation of both oil-in-water and water-in-oil emulsion droplets.
    • Accurate detection of droplet size using integrated microelectrodes.

    Conclusions:

    • The presented technology offers improved integration of microfluidics by directly embedding components onto printed circuit boards.
    • This approach simplifies fabrication and enhances the potential for incorporating microfluidics into complex MEMS.
    • The chip serves as a promising platform for microfluidic applications requiring integrated sensing and control.