Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Carbon Skeletons

Carbon Skeletons

Life on Earth is carbon-based, as all macromolecules that make up living organisms contain carbon atoms. All organic compounds have a carbon backbone. Each carbon atom is tetravalent and can bond with four other atoms, making it an extraordinarily flexible component of biological molecules. Because carbon’s valence electrons are stable, it rarely becomes an ion. As the carbon chain increases in length, structural modifications such as ring structures, double bonds, and branching side...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Impact of intravenous thrombolysis on aspiration thrombectomy outcomes: an Imperative Trial subgroup analysis.

Journal of neurointerventional surgery·2026

Same author

The Fate of the Middle Meningeal Artery in Patients with Chronic Subdural Hematoma Treated with Embolization.

World neurosurgery·2026

Same author

Cost-Effectiveness of Adjunctive Middle Meningeal Artery Embolization for Chronic Subdural Hematoma: Secondary Analysis of EMBOLISE.

AJNR. American journal of neuroradiology·2026

Same author

Development, image interpretation, clinical experience, and applications of optical coherence tomography in neurointerventional surgery.

Journal of neurointerventional surgery·2026

Same author

Frontline aspiration versus stent retriever thrombectomy for M2 occlusions: Insights from the STAR registry.

European stroke journal·2026

Same author

Large-Vessel Occlusion Stroke Knowledge and Training for Stroke Severity Assessment Among Emergency Medical Services Personnel in the United States.

Stroke (Hoboken, N.J.)·2026

Same journal

Non-contact Heart Sound Measurement by Defocused Speckle Imaging.

IEEE journal of biomedical and health informatics·2026

Same journal

TaxEL: Taxonomy-Enhanced Entity Representation Learning for Biomedical Entity Linking.

IEEE journal of biomedical and health informatics·2026

Same journal

Multimodal Feature Prototype Learning for Interpretable and Discriminative Cancer Survival Prediction.

IEEE journal of biomedical and health informatics·2026

Same journal

CrossSG-DTA: Synergizing Sequence Semantics and Graph Structures via Cross-Attention for Drug-Target Affinity Prediction.

IEEE journal of biomedical and health informatics·2026

Same journal

FGCSA-Net: A Novel Framework for Medical Report Generation Via Fine-Grained Feature Preservation and Semantic Alignment.

IEEE journal of biomedical and health informatics·2026

Same journal

Med-SORA: Symptom to Organ Reasoning in Abdomen CT Images.

IEEE journal of biomedical and health informatics·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 4, 2026

An In Vitro 3D Model and Computational Pipeline to Quantify the Vasculogenic Potential of iPSC-Derived Endothelial Progenitors

An In Vitro 3D Model and Computational Pipeline to Quantify the Vasculogenic Potential of iPSC-Derived Endothelial Progenitors

Published on: May 13, 2019

3-D vascular skeleton extraction and decomposition.

Ashirwad Chowriappa, Yong Seo, Sarthak Salunke

IEEE Journal of Biomedical and Health Informatics

|January 10, 2014

Summary

This summary is machine-generated.

This study presents a new method for extracting and decomposing vascular skeletons, improving computer-assisted diagnosis. The technique accurately decomposes vessels and identifies skeletal branches, aiding in aneurysm analysis.

More Related Videos

Three and Four-Dimensional Visualization and Analysis Approaches to Study Vertebrate Axial Elongation and Segmentation

Three and Four-Dimensional Visualization and Analysis Approaches to Study Vertebrate Axial Elongation and Segmentation

Published on: February 28, 2021

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model

Published on: March 16, 2022

Related Experiment Videos

Last Updated: May 4, 2026

An In Vitro 3D Model and Computational Pipeline to Quantify the Vasculogenic Potential of iPSC-Derived Endothelial Progenitors

An In Vitro 3D Model and Computational Pipeline to Quantify the Vasculogenic Potential of iPSC-Derived Endothelial Progenitors

Published on: May 13, 2019

Three and Four-Dimensional Visualization and Analysis Approaches to Study Vertebrate Axial Elongation and Segmentation

Three and Four-Dimensional Visualization and Analysis Approaches to Study Vertebrate Axial Elongation and Segmentation

Published on: February 28, 2021

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model

Published on: March 16, 2022

Area of Science:

Medical Imaging
Computer-Aided Diagnosis
Vascular Analysis

Background:

Accurate vascular decomposition and skeleton extraction are crucial for computer-assisted diagnosis and analysis of vascular diseases.
Existing methods may face challenges in precision and efficiency for complex vascular structures.

Purpose of the Study:

To introduce a novel technique for vascular skeleton extraction and decomposition.
To enhance computer-assisted diagnosis and analysis of vascular structures, particularly in the context of aneurysms.

Main Methods:

Vascular decomposition addressed as a cluster optimization problem using weighted convex approximations.
Vessel skeleton extraction performed using a Laplace-based operator.
Method validated on presegmented vasculature from 98 aneurysms in 112 patients and longitudinal data.

Main Results:

Achieved an estimated 80.5% accuracy in vascular decomposition.
Identified the correct number of skeletal branches in 92.9% of vessel sections, validated by a clinical radiological expert.
Demonstrated ability to detect changes in aneurysm volumes and surface areas comparable to expert segmentation.

Conclusions:

The proposed method offers a promising approach for accurate vascular skeleton extraction and decomposition.
This technique can significantly aid in the computer-assisted diagnosis and analysis of vascular conditions like aneurysms.
The validated results suggest potential for improved quantitative analysis of vascular changes over time.