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The Retina

The Retina

The retina is a layer of nervous tissue at the back of the eye that transduces light into neural signals. This process, called phototransduction, is carried out by rod and cone photoreceptor cells in the back of the retina.

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Related Experiment Video

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Techniques for Processing Eyes Implanted with a Retinal Prosthesis for Localized Histopathological Analysis: Part 2 Epiretinal Implants with Retinal Tacks

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Retinal implants: a systematic review.

Alice T Chuang, Curtis E Margo, Paul B Greenberg

The British Journal of Ophthalmology

|January 10, 2014

Summary

This summary is machine-generated.

This review compares five retinal prostheses for vision restoration. Alpha-IMS shows the most promise for long-term success in treating degenerative retinal diseases.

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Area of Science:

Ophthalmology
Biomedical Engineering
Medical Devices

Background:

Degenerative retinal diseases cause vision loss.
Retinal implants offer a potential solution for sight restoration.
Previous reviews were device-specific; an objective comparison is needed.

Purpose of the Study:

To systematically compare five representative retinal prostheses.
To evaluate clinical availability, vision restoration potential, and long-term biocompatibility.
To identify the most promising retinal implant for future success.

Main Methods:

Systematic review of publications on Argus II, Boston Retinal Implant Project, Epi-Ret 3, Intelligent Medical Implants (IMI), and Alpha-IMS.
Analysis based on clinical availability, vision restoration, and long-term biocompatibility.
Comparison of device features like electrode count, camera systems, and biocompatibility.

Main Results:

Argus II has FDA approval; Argus II and Alpha-IMS have CE Marking.
Boston Retinal Implant has 100 electrodes; Alpha-IMS achieves visual acuity up to 20/546.
Alpha-IMS utilizes a unique photodiode system and intraocular photosensitive elements.

Conclusions:

Alpha-IMS demonstrates significant potential for long-term success in retinal prostheses.
The device's design may offer advantages beyond current clinical availability.
Further research and development in retinal implant technology are crucial.