Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Alzheimer Disease l: Introduction01:29

Alzheimer Disease l: Introduction

21
Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
21
Meiosis I01:49

Meiosis I

176.7K
Meiosis is a carefully orchestrated set of cell divisions, the goal of which—in humans—is to produce haploid sperm or eggs, each containing half the number of chromosomes present in somatic cells elsewhere in the body. Meiosis I is the first such division, and involves several key steps, among them: condensation of replicated chromosomes in diploid cells; the pairing of homologous chromosomes and their exchange of information; and finally, the separation of homologous chromosomes by...
176.7K
Karyotyping01:17

Karyotyping

49.3K
Overview
49.3K
Learning Disabilities01:25

Learning Disabilities

697
Learning disabilities are cognitive disorders caused by neurological impairments that affect cognitive functions like language and reading, without indicating overall intellectual or developmental challenges. These disabilities differ from global intellectual or developmental disabilities as they are limited to distinct cognitive functions. Common learning disabilities include dysgraphia, dyslexia, and dyscalculia, each of which impacts unique aspects of learning.
Dyslexia
Dyslexia is a...
697
Nondisjunction01:29

Nondisjunction

7.6K
7.6K
Nondisjunction01:29

Nondisjunction

68.0K
During meiosis, chromosomes occasionally separate improperly. This occurs due to failure of homologous chromosome separation during meiosis I or failed sister chromatid separation during meiosis II. In some species, notably plants, nondisjunction can result in an organism with an entire additional set of chromosomes, which is called polyploidy. In humans, nondisjunction can occur during male or female gametogenesis and the resulting gametes possess one too many or one too few chromosomes.
68.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Charles McBurney, American pioneer of appendicectomy.

Journal of perioperative practiceยท2022
Same author

Baron Guillaume Dupuytren and his contracture.

Journal of perioperative practiceยท2022
Same author

John Hunter, excision of a massive parotid tumour.

Journal of perioperative practiceยท2022
Same author

Ligation of the common carotid artery.

Journal of perioperative practiceยท2022
Same author

Instructive mistakes.

Journal of perioperative practiceยท2022
Same author

The first open cardiac operation.

Journal of perioperative practiceยท2022

Related Experiment Video

Updated: May 4, 2026

In Vitro Modeling of Down Syndrome Neurogenesis Using Human-Induced Pluripotent Stem Cells
06:38

In Vitro Modeling of Down Syndrome Neurogenesis Using Human-Induced Pluripotent Stem Cells

Published on: March 7, 2025

1.1K

John Langdon Down: Down's syndrome.

Harold Ellis1

  • 1Department of Anatomy, University of London, Guy's Campus, London, SE1 1UL.

Journal of Perioperative Practice
|January 11, 2014
PubMed
Summary
This summary is machine-generated.

Medical students in the 1940s commonly encountered patients with

More Related Videos

Author Spotlight: Validation of SICOLE-R for Assessing Cognitive and Reading Skills in Spanish-Speaking Children and Its Role in Personalized Education
09:00

Author Spotlight: Validation of SICOLE-R for Assessing Cognitive and Reading Skills in Spanish-Speaking Children and Its Role in Personalized Education

Published on: August 16, 2024

1.3K
Examining Recall Memory in Infancy and Early Childhood Using the Elicited Imitation Paradigm
06:35

Examining Recall Memory in Infancy and Early Childhood Using the Elicited Imitation Paradigm

Published on: April 28, 2016

34.3K

Related Experiment Videos

Last Updated: May 4, 2026

In Vitro Modeling of Down Syndrome Neurogenesis Using Human-Induced Pluripotent Stem Cells
06:38

In Vitro Modeling of Down Syndrome Neurogenesis Using Human-Induced Pluripotent Stem Cells

Published on: March 7, 2025

1.1K
Author Spotlight: Validation of SICOLE-R for Assessing Cognitive and Reading Skills in Spanish-Speaking Children and Its Role in Personalized Education
09:00

Author Spotlight: Validation of SICOLE-R for Assessing Cognitive and Reading Skills in Spanish-Speaking Children and Its Role in Personalized Education

Published on: August 16, 2024

1.3K
Examining Recall Memory in Infancy and Early Childhood Using the Elicited Imitation Paradigm
06:35

Examining Recall Memory in Infancy and Early Childhood Using the Elicited Imitation Paradigm

Published on: April 28, 2016

34.3K

Area of Science:

  • Medical History
  • Genetics
  • Developmental Pediatrics

Background:

  • Historical context of 'Mongolism' (now Down syndrome) in medical education.
  • Early observations of individuals with Down syndrome in pediatric and psychiatric settings.
  • The societal and medical understanding of the condition during the mid-20th century.

Discussion:

  • The evolution of terminology from 'Mongolism' to Down syndrome.
  • The impact of historical terminology on patient perception and stigma.
  • Reflections on the long-term care and institutionalization of individuals with Down syndrome.

Key Insights:

  • 'Mongolism' was a common diagnostic term in the 1940s.
  • Individuals with this condition were seen across various medical specialities.
  • Lifelong institutionalization was a frequent outcome for patients.

Outlook:

  • Understanding historical medical terminology is crucial for modern medical ethics.
  • The shift in language reflects evolving societal attitudes towards genetic conditions.
  • Continued research into Down syndrome aims to improve quality of life and reduce stigma.