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Cerebral palsy risk factors and their impact on psychopathology

Anat Levy-Zaks, Yehuda Pollak, Hilla Ben-Pazi

    Neurological Research
    |January 11, 2014
    PubMed

    Insights

    The cause of brain injury does not affect the emotional and behavioral symptoms or quality of life in children with cerebral palsy (CP). Children with CP experience more challenges than their siblings.

    Area of Science:

    • Neuroscience
    • Pediatrics
    • Developmental Psychology

    Background:

    • Cerebral palsy (CP) is a group of disorders affecting movement and posture, often resulting from brain injury.
    • Understanding the impact of different brain injury etiologies on psychopathology and quality of life in children with CP is crucial for targeted interventions.

    Purpose of the Study:

    • To investigate if the type of brain injury (prematurity vs. asphyxia at term) influences the psychopathological profile and quality of life in children with cerebral palsy.
    • To compare the psychopathological profile and quality of life of children with CP to their unaffected siblings.

    Main Methods:

    • A cohort of 18 children with CP (9 born prematurely, 9 with birth asphyxia) and 16 siblings were assessed.
    • Parent-reported data were collected using the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Rating Scale (DBDRS), and Pediatric Quality of Life Inventory (PedsQL).

    Main Results:

    • Children with CP exhibited significantly higher levels of emotional and behavioral symptoms, including depression, anxiety, and problems with social interaction, thought processes, and attention, compared to their siblings.
    • Quality of life was notably lower in children with CP than in their siblings.
    • The psychopathological profiles of children with CP resulting from prematurity and birth asphyxia were found to be similar.

    Conclusions:

    • The etiology of brain injury in children with cerebral palsy does not appear to influence their psychopathological profile.
    • Children with CP face significant emotional, behavioral, and quality of life challenges regardless of the cause of their brain injury.
    Abstract

    Keywords:
    Cerebral palsy,Hypoxic-ischemic encephalopathy,Periventricular leukomalacia,Psychopathology,Quality of life

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