Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pseudoglandular hepatocellular carcinoma. A morphogenetic study.

Y Kondo, T Nakajima

    Cancer
    |September 1, 1987
    PubMed
    Summary

    This study examines pseudoglandular formations in hepatocellular carcinoma (HCC), identifying dilated bile canaliculi as the primary source. Recognizing these diverse HCC appearances is crucial for accurate hepatic tumor diagnosis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Different antigenic nature in apparently healthy women with high serum CA 125 levels compared with typical patients with ovarian cancer.

    Cancer·1992
    Same author

    Paraneoplastic cerebellar degeneration: successful early detection and treatment of cancer through characterization of the anti-Purkinje cell antibody.

    Internal medicine (Tokyo, Japan)·1992
    Same author

    Comparison of specific reactivity of monoclonal and polyclonal ABH reactive antibodies.

    Nihon hoigaku zasshi = The Japanese journal of legal medicine·1992
    Same author

    A novel method for blood group typing with the aid of monoclonal antibody immobilized dyed microspheres.

    Nihon hoigaku zasshi = The Japanese journal of legal medicine·1992
    Same author

    Detection of human papillomavirus DNA in invasive cervical cancers by the polymerase chain reaction and its clinical significance.

    Acta pathologica japonica·1992
    Same author

    Hepatocellular carcinoma containing endocrine cells. An autopsy report of triplecancer involving the liver, kidney and thyroid.

    Acta pathologica japonica·1992

    Area of Science:

    • Hepatobiliary Pathology
    • Surgical Pathology
    • Oncology

    Background:

    • Hepatocellular carcinoma (HCC) exhibits diverse histopathologic features.
    • Pseudoglandular formation can mimic other liver tumors, complicating diagnosis.

    Purpose of the Study:

    • To investigate the origins and characteristics of pseudoglandular formations in HCC.
    • To emphasize the diagnostic importance of recognizing varied HCC manifestations.

    Main Methods:

    • Histopathologic examination of 39 selected HCC cases.
    • Analysis of pseudoglandular formation origins, including bile canaliculi dilatation and tumor cell necrosis.
    • Comparison with cholangiocarcinoma and metastatic adenocarcinomas.

    Main Results:

    • Dilated bile canaliculi were the most common source of pseudoglands (28/39 cases).
    • Tumor cell necrosis accounted for pseudoglandular formation in 6/39 cases.
    • Microglandular formation mimicking cholangiocarcinoma was observed in 5 cases.

    Conclusions:

    • Variable pseudoglandular patterns in HCC can arise from dilated bile canaliculi or tumor necrosis.
    • Distinguishing HCC with pseudoglandular features from other hepatic malignancies is essential for correct diagnosis.
    • Combined HCC and cholangiocarcinoma cases showed mucin positivity, differentiating them from pure HCC.

    Related Experiment Videos