Related Experiment Video

Updated: May 4, 2026

A Murine Model of Hemodialysis Access-Related Hand Dysfunction
08:39

A Murine Model of Hemodialysis Access-Related Hand Dysfunction

Published on: May 31, 2022

1.8K

Anatomical factors associated with left innominate vein stenosis in hemodialysis patients

Yaxue Shi1, Jiejun Cheng, Yanyan Song

  • 1Department of Vascular Surgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Hemodialysis International. International Symposium on Home Hemodialysis
|January 11, 2014
PubMed

Insights

Left innominate vein stenosis in hemodialysis patients may stem from anatomical compression. Narrowing between the sternum and aortic arch is linked to this condition, suggesting CT scans can help identify it.

Area of Science:

  • Vascular Surgery
  • Nephrology
  • Radiology

Background:

  • Central venous stenosis is a significant complication for patients undergoing hemodialysis.
  • Left innominate vein (LIV) stenosis is frequently observed, often near the aortic arch, suggesting potential anatomical causes like extrinsic compression.

Purpose of the Study:

  • To investigate whether anatomical compression, specifically related to the aortic arch and sternum, contributes to the development of left innominate vein stenosis in hemodialysis patients.

Main Methods:

  • A cohort of 19 hemodialysis patients with symptomatic upper-left extremity venous hypertension was studied.
  • Venography and multidetector computed tomography (MDCT) were employed to assess LIV anatomy and stenosis.
  • Measurements of LIV diameter and the retrosternal space (aortic arch to sternum) were compared between patients with and without LIV stenosis.

Main Results:

  • Patients with LIV stenosis exhibited a significantly smaller space between the aortic arch and sternum (4.55 mm) compared to those without stenosis (15.25 mm).
  • The mean LIV diameter was markedly reduced in the LIV stenosis group (1.69 mm) versus the non-stenosis group (8.71 mm).
  • A smaller retrosternal space was strongly correlated with the presence of LIV stenosis (P < 0.001).

Conclusions:

  • Anatomical compression of the left innominate vein by the aortic arch behind the sternum is a likely contributing factor to LIV stenosis in hemodialysis patients.
  • Preoperative noncontrast computed tomography is recommended to evaluate for extrinsic compression in hemodialysis patients presenting with potential LIV stenosis.

Keywords:
Left innominate vein stenosisanatomical factorshemodialysismultidetector CT

More Related Videos

Murine Model of Central Venous Stenosis using Aortocaval Fistula with an Outflow Stenosis06:17

Murine Model of Central Venous Stenosis using Aortocaval Fistula with an Outflow Stenosis

Published on: July 11, 2019

6.9K
Deep Vein Thrombosis Induced by Stasis in Mice Monitored by High Frequency Ultrasonography06:44

Deep Vein Thrombosis Induced by Stasis in Mice Monitored by High Frequency Ultrasonography

Published on: April 13, 2018

9.6K

Related Concept Videos

Hemodialysis I: Introduction01:25

Hemodialysis I: Introduction

Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
4.0K
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
469
Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
2.2K
Hemodialysis III: Nursing Management01:25

Hemodialysis III: Nursing Management

The nursing management of a patient undergoing hemodialysis includes several critical steps, starting with a thorough assessment before the procedure.Before the Hemodialysis ProcedureFirst, record the patient's vital signs—blood pressure, heart rate, respiratory rate, and temperature—to establish a baseline. This baseline is essential for detecting conditions such as hypotension that could impact the patient's response to dialysis. Document the patient's pre-dialysis weight, as this...
1.8K
Veins of the Abdomen and Pelvis01:18

Veins of the Abdomen and Pelvis

The human body is a complex system of interconnected parts, and the circulatory system plays a crucial role in maintaining overall health. One key component of this system is the inferior vena cava, a large vein responsible for returning blood from the abdominopelvic viscera and abdominal walls to the heart.
The inferior vena cava is fed by numerous smaller veins. The lumbar veins, for instance, drain the posterior abdominal wall, emptying both directly into the inferior vena cava and into the...
2.2K
Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
558