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X-marks the spot: X-chromosome identification during dosage compensation

Jessica Chery1, Erica Larschan1

  • 1Department of Molecular Biology, Cellular Biology, and Biochemistry, Brown University, 185 Meeting Street, Providence, RI 02912, USA.

Biochimica Et Biophysica Acta
|January 11, 2014
PubMed
Summary

Dosage compensation equalizes X-linked gene dosage between sexes. This process, involving long non-coding RNAs and DNA elements, provides insights into coordinated gene regulation and X-chromosome targeting.

Keywords:
C. elegansDosage compensationDrosophilaMammals

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