Patient-specific implants compared with stored bone grafts for patients with interval cranioplasty

Interval cranioplasty after craniectomy carries the risk of infection and failure. There is no consensus regarding the choice of reconstruction technique. In addition to the replacement of the stored autogenous bone graft, the use of patient-specific implants (PSIs) has become popular. We conducted a retrospective study comparing 17 patients who underwent reconstruction with PSIs (titanium and polyether ether ketone) (follow-up, 43 months [range, 3-93]) with 16 control subjects who had their stored bone grafts reimplanted (follow-up, 32 months [range, 5-92]) based on success rate, complication rate, operative time, and duration of hospitalization. Complication rate and the rate of necessary reoperation were significantly lower, and the hospital stay was shorter in the PSI group. We did not find any significant differences concerning operative time. In our patient groups, interval reconstruction after craniectomy with a PSI was a safer procedure based on complication and success rates than reconstruction with stored autogenous bone grafts. In patients with interval cranioplasty who have a higher risk for complication or failure, the use of PSIs should be the treatment of choice.