Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Evaluation of lung epithelial permeability.

M I Newhouse, M Jordana, M Dolovich

    European Journal of Nuclear Medicine
    |January 1, 1987
    PubMed
    Summary

    Researchers identified factors influencing 99mTc-DTPA absorption across the alveolar-capillary membrane. This enhances understanding of lung epithelial permeability (LEP) measurements and their clinical applications.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    IgG1<sup>+</sup> B-cell immunity predates IgE responses in epicutaneous sensitization to foods.

    Allergy·2018
    Same author

    Anatomical Description of the Presence and Variability of the Digital Manica Flexoria in the Equine Digital Flexor Tendon Sheath.

    Anatomia, histologia, embryologia·2016
    Same author

    Diffusion of mepivacaine to adjacent synovial structures after intrasynovial analgesia of the digital flexor tendon sheath.

    Equine veterinary journal·2015
    Same author

    Comprehensive metabolomics identifies the alarmin uric acid as a critical signal for the induction of peanut allergy.

    Allergy·2015
    Same author

    T helper cell IL-4 drives intestinal Th2 priming to oral peanut antigen, under the control of OX40L and independent of innate-like lymphocytes.

    Mucosal immunology·2014
    Same author

    Pulmonary M. tuberculosis infection delays Th1 immunity via immunoadaptor DAP12-regulated IRAK-M and IL-10 expression in antigen-presenting cells.

    Mucosal immunology·2013

    Area of Science:

    • Pulmonary medicine
    • Medical imaging
    • Physiology

    Background:

    • The alveolar-capillary membrane is crucial for gas exchange.
    • Lung epithelial permeability (LEP) measurements offer insights into lung health.
    • Technetium-99m diethylenetriamine penta-acetic acid (99mTc-DTPA) is a radiotracer used to assess LEP.

    Purpose of the Study:

    • To identify factors affecting 99mTc-DTPA absorption rate.
    • To understand the significance and limitations of LEP measurements.
    • To review studies of pulmonary 99mTc-DTPA absorption in various clinical conditions.

    Main Methods:

    • Measurement of 99mTc-DTPA absorption rate.
    • Identification of influencing factors.
    • Review of clinical studies.

    Main Results:

    • Several factors affecting 99mTc-DTPA absorption have been identified.
    • These factors provide insights into the significance of LEP measurements.
    • Potential limitations of LEP measurements have been highlighted.

    Conclusions:

    • Understanding factors influencing 99mTc-DTPA absorption is key to accurate LEP assessment.
    • LEP measurements have significant clinical relevance but also limitations.
    • Further research and standardized methods are needed for reliable clinical application.

    Related Experiment Videos