Acute coronary syndrome among older patients: a review
Murugapathy Veerasamy1, Richard Edwards, Gary Ford
1From the *Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; †Cardiothoracic Centre, Freeman Hospital, Newcastle upon Tyne, United Kingdom; and ‡Institute of Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom.
Insights
Acute coronary syndrome is a major cause of death in older adults, often linked to comorbidities. This review highlights frailty assessment as crucial for future research and treatment strategies in this population.
Area of Science:
- Cardiology
- Geriatrics
- Public Health
Background:
- Ischemic heart disease is the leading global cause of mortality.
- Increased life expectancy results in an aging population worldwide.
- Older adults experience higher morbidity and mortality from acute coronary syndrome due to comorbidities.
Purpose of the Study:
- To review the incidence and prevalence of acute coronary syndrome in older patients.
- To examine current treatment strategies for acute coronary syndrome in the elderly.
- To evaluate predictors of adverse outcomes, focusing on frailty.
Main Methods:
- Literature review of studies on acute coronary syndrome in older adults.
- Analysis of treatment strategies and outcome predictors.
- Discussion on the impact of frailty and the need for its assessment.
Main Results:
- Acute coronary syndrome poses a significant threat to the aging population.
- Age-related comorbidities exacerbate the impact of acute coronary syndrome.
- Frailty is a key factor influencing adverse outcomes in older patients.
Conclusions:
- Frailty assessment is essential for managing acute coronary syndrome in older patients.
- Future research and clinical strategies must incorporate frailty assessment.
- Improved management strategies are needed to address the challenges of acute coronary syndrome in the elderly.
Abstract:
Ischemic heart disease is the leading cause of mortality worldwide. Due to advances in medicine in the past few decades, life expectancy has increased resulting in an aging population in developed and developing countries. Acute coronary syndrome causes greater morbidity and mortality in this group of older patients, which appears to be due to age-related comorbidities. This review examines the incidence and prevalence of acute coronary syndrome among older patients, examines current treatment strategies, and evaluates the predictors of adverse outcomes. In particular, the impact of frailty on outcomes and the need for frailty assessment in developing future research and management strategies among older patients are discussed.
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