Breast and subcutaneous plasmoblastic infiltrations in the course of plasmoblastoma

In two female patients aged 37 and 66 y breast and subcutaneous plasmoblastic infiltrations developed in the course of therapy for plasmoblastoma. In the first patient with plasmoblastic leukemia those infiltrations occurred after 6-month therapy. In the second patient progression of the disease was noted after 30 months of treatment. Both multiple osteolytic lesions as well as breast and subcutaneous plasmoblastic infiltrations were noticed that time. Multidrug treatment programme had little influence on those infiltrations.