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Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
Published on: February 9, 2024
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Value of strain-ratio on thyroid real-time sonoelastography.
Manlio Guazzaroni1, Alessio Spinelli, Irene Coco
1Dipartimento di Diagnostica per Immagini, Imaging Molecolare, Radiologia Interventistica e Radioterapia, Fondazione Policlinico Universitario "Tor Vergata", Viale Oxford 81, 00133, Rome, Italy.
La Radiologia Medica
|January 11, 2014
Summary
Elastosonography accurately diagnoses thyroid nodules. The stiffness score (SS) showed high sensitivity (91%) and negative predictive value (98%), outperforming the strain ratio (SR).
Area of Science:
- Medical Imaging
- Diagnostic Ultrasound
- Endocrinology
Background:
- Thyroid nodules are common, requiring accurate diagnostic methods.
- Elastosonography offers a non-invasive approach to assess nodule stiffness.
- Differentiating benign from malignant thyroid nodules is crucial for patient management.
Purpose of the Study:
- To evaluate the diagnostic accuracy of elastosonography for thyroid nodules.
- To compare qualitative stiffness score (SS) and quantitative strain ratio (SR) assessments.
- To determine the utility of elastosonography in the differential diagnosis of thyroid nodules.
Main Methods:
- Retrospective analysis of 368 patients with thyroid nodules.
- Conventional ultrasonography and elastosonography were performed.
- Stiffness score (SS) and strain ratio (SR) were assessed, followed by needle aspiration.
Main Results:
- Malignancy confirmed in 44 nodules, benign in 324.
- Stiffness score (SS) > 2 yielded 91% sensitivity and 98% negative predictive value (NPV).
- Strain ratio (SR) ≥ 3.28 showed 81.8% sensitivity and 97.1% NPV.
Conclusions:
- Stiffness score (SS) is a reliable elastosonography benchmark for thyroid nodules.
- Strain ratio (SR) did not add significant diagnostic value beyond SS.
- Larger prospective trials are needed to validate these findings.
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