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Published on: February 28, 2015
DNA nanocages swallow gold nanoparticles (AuNPs) to form AuNP@DNA cage core-shell structures
Chuan Zhang1, Xiang Li, Cheng Tian
1Department of Chemistry and ‡Markey Center for Structural Biology and Department of Biological Sciences, Purdue University , West Lafayette, Indiana 47907, United States.
Abstract:
DNA offers excellent programming properties to nanomaterials syntheses. Host-guest interaction between DNA nanostructures and inorganic nanoparticles (NPs) is of particular interest because the resulting complexes would possess both programming properties intrinsic to DNA and physical properties associated with inorganic NPs, such as plasmonic and magnetic features. Here, we report a class of core-shell complexes (AuNP@DNA cages): hard gold NPs (AuNPs) are encapsulated in geometrically well-defined soft DNA nanocages. The AuNP guest can be further controllably released from the host (DNA nanocages), pointing to potential applications in surface engineering of inorganic NPs and cargo delivery of DNA nanocages.
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