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Updated: May 4, 2026

Increased Recovery Time and Decreased LPS Administration to Study the Vagus Nerve Stimulation Mechanisms in Limited Inflammatory Responses
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The cholinergic anti-inflammatory pathway: a critical review

D Martelli1, M J McKinley2, R M McAllen3

  • 1Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria 3010, Australia; Department of Biomedical and Neuromotor Sciences, Physiology Division, University of Bologna, Italy.

Autonomic Neuroscience : Basic & Clinical
|January 14, 2014
PubMed
Summary

Electrical vagus nerve stimulation suppresses inflammation by acting on the spleen. This pathway involves T lymphocytes and nicotinic receptors, highlighting a non-neural anti-inflammatory mechanism.

Keywords:
Vagus inflammation reflex

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