Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Archival Research01:40

Archival Research

15.6K
Some researchers gain access to large amounts of data without interacting with a single research participant. Instead, they use existing records to answer various research questions. This type of research approach is known as archival research. Archival research relies on looking at past records or data sets to look for interesting patterns or relationships. For example, a researcher might access the academic records of all individuals who enrolled in college within the past ten years and...
15.6K
Ethics in Research01:56

Ethics in Research

23.7K
Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
23.7K
Strategies for Assessing and Addressing Confounding01:25

Strategies for Assessing and Addressing Confounding

596
Confounding is a critical issue in epidemiological studies, often leading to misleading conclusions about associations between exposures and outcomes. It occurs when the relationship between the exposure and the outcome is mixed with the effects of other factors that influence the outcome. Given that, addressing confounding is of high importance for drawing accurate inferences in research.
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
596
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

627
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
627
Improving Translational Accuracy02:07

Improving Translational Accuracy

11.6K
Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
11.6K
Improving Translational Accuracy02:07

Improving Translational Accuracy

2.6K
2.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development and acceptability of gist-based decision aids for prostate and breast cancer screening: a two-phase qualitative interview study in an online setting.

BMJ open·2026
Same author

Measurement of ethnicity in clinical trials: Delphi survey and consensus statement.

BMJ (Clinical research ed.)·2026
Same author

Patient Engagement With an Electronic Patient-Reported Outcomes Tool Evaluating Hospital Discharge Readiness After Cancer Surgery.

JCO oncology practice·2026
Same author

Nerve Blocks for Mastectomy with Reconstruction: Reply.

Anesthesiology·2026
Same author

Protocol for a SPIRIT extension for reporting Pragmatic and Explanatory trial protocols designed using the PRECIS tool. (SPIRIT-PRECIS).

Journal of clinical epidemiology·2026
Same author

SPIRIT 2025 statement: updated guideline for protocols of randomised trials.

Lancet (London, England)·2026

Related Experiment Video

Updated: May 4, 2026

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

14.4K

Increasing value and reducing waste: addressing inaccessible research.

An-Wen Chan1, Fujian Song2, Andrew Vickers3

  • 1Women's College Research Institute, Department of Medicine, Women's College Hospital, University of Toronto, Toronto, ON, Canada.

Lancet (London, England)
|January 14, 2014
PubMed
Summary
This summary is machine-generated.

Health research dissemination is poor, with limited access to protocols, reports, and data. This leads to wasted investment and biased results, harming patient care and research progress.

More Related Videos

Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms
10:41

Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms

Published on: May 9, 2017

9.9K
Harvesting and Disaggregation: An Overlooked Step in Biofilm Methods Research
13:25

Harvesting and Disaggregation: An Overlooked Step in Biofilm Methods Research

Published on: April 22, 2022

4.1K

Related Experiment Videos

Last Updated: May 4, 2026

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

14.4K
Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms
10:41

Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms

Published on: May 9, 2017

9.9K
Harvesting and Disaggregation: An Overlooked Step in Biofilm Methods Research
13:25

Harvesting and Disaggregation: An Overlooked Step in Biofilm Methods Research

Published on: April 22, 2022

4.1K

Area of Science:

  • Health Research
  • Biomedical Research
  • Clinical Trials

Background:

  • Health research documentation includes protocols, full reports, and datasets.
  • These essential documents are rarely available, leading to incomplete information.
  • Journal reports are often selectively reported and incomplete, hindering research reproducibility.

Purpose of the Study:

  • To highlight the critical issue of inaccessible health research data.
  • To underscore the negative consequences of poor data dissemination.
  • To propose systemic solutions for improving research transparency and data sharing.

Main Methods:

  • The study is a review and analysis of current practices in health research documentation and dissemination.
  • It examines the availability and quality of study protocols, full study reports, and participant-level datasets.
  • It identifies systemic barriers and proposes actionable recommendations.

Main Results:

  • Protocols, full study reports, and participant-level datasets are seldom accessible.
  • Available journal reports suffer from selective reporting and methodological omissions.
  • Incomplete data access results in billions of dollars in wasted investment and introduces bias.

Conclusions:

  • Academic institutions and funders must incentivize full research dissemination.
  • Developing and adopting rigorous standards for protocols, reports, and data sharing is crucial.
  • Journals, funders, and regulators should enforce policies for study registration and data availability.